| The results from the initial laboratory testing will help to
determine which candidates move through to the next step of development.
However, other factors also need to be considered as drugs move
forward in development. These include:
-
Whether the drug is better than existing drugs
-
How easy it is to manufacture
-
How easy it is to formulate
-
How long it will take to develop
-
What regulatory hurdles there may be
-
How stable the drug will be
-
What the cost is likely to be
-
Whether use of the drug is likely to generate drug resistant
HIV
-
How safe and effective the drug is
|
Taking all these into consideration, EMPRO will select microbicide
drug candidates based on the best available scientific evidence,
in line with the principles of rational drug development and in
context with the global microbicide effort. The best candidate(s)
generated by EMPRO that fulfil EMPRO's selection criteria are expected
to enter into clinical testing in the later stages of the project.
A typical nanocluster that will be used by EMPRO to develop microbicides
|
